Hydroxypinacolone Retinoate
Hydroxypinacolone Retinoate (HPR) Powder is a unique derivative of retinoic acid, the ingredient be sold under product name”Granactive Retinoid”. Hydroxypinacolone Retinoate (HPR) is a cosmetic grade ester of ATRA, the unique is that it processes innate retinoic acid activity, do not need to undergo metabolic breakdown that can achieve skin benefits.
| Name | Hydroxypinacolone Retinoate |
| Synonyms | BENZAMIDE, 4-BROMO-2-FLUORO-N-(1-METHYL-4-PIPERIDINYL)-; |
| Appearance | Yellow powder or crystal |
| Form | Solid |
| CAS | 893412-73-2 |
| Assay | 98%min(PHLC) |
| Solubility | insoluble in water |
| Boiling point | 508.5±33.0 °C(Predicted) |
| Heavy metal | ≤20ppm |
| Storage Temp | Store at -20°C |
| Molecular Formula | C26H38O3 |
| Molecular Weight | 398.58 |
| Shelf life | 2 years |
| Application | Cosmetics Ingredient |
| Grade | Cosmetics & Pharmaceuticals grade |
What is Hydroxypinacolone Retinoate Powder
Hydroxypinacolone Retinoate (HPR) Powder is a unique derivative of retinoic acid, the ingredient be sold under product name”Granactive Retinoid”. Hydroxypinacolone Retinoate (HPR) is a cosmetic grade ester of ATRA, the unique is that it processes innate retinoic acid activity, do not need to undergo metabolic breakdown that can achieve skin benefits. Hydroxypinacolone Retinoate (HPR) have proved with more stable and cause less skin irritation than ATRA. In addition, compared the antiaging properties of Hydroxypinacolone Retinoate (HPR) to ATRA by testing the effects on collagen levels and skin irritation in organotypic skin models. The results suggest that Hydroxypinacolone Retinoate (HPR) is an effective alternative to ATRA and other less potent retinoids in the treatment of aging skin without the detrimental side effects, and improve the appearance of aging skin without the irritation. It also can provide same results to the skin as retinoic acid when applied(no conversion needed, remember) but without the irritation. According to Hydroxypinacolone Retinoate (HPR) powder manufacturer’s tests, 24 hours of an occlusive patch with 0.5% HPR resulted in significantly lower irritation than 0.5% retinol. And, Hydroxypinacolone Retinoate (HPR) is available over the counter in the EU, UK, Asia, New Zealand and Australia, but is only with a prescription in Canada.
Hydroxypinacolone Retinoate Powder Usage
Hydroxypinacolone Retinoate powder have function of regulating the metabolism of the epidermis and stratum corneum, can resist aging, can reduce sebum spillage, dilute the epidermal pigment, play a role in preventing skin aging, preventing acne, whitening and bright spots. While ensuring the powerful efficacy of retinol, it also greatly reduces its irritation. It is currently used for anti-aging and prevention of acne recurrence.
What’s Effect Of Hydroxypinacolone Retinoate Powder
1) No risk of adverse reactions, low stimulation
2) Higher activity
3) Better stability
4) Due to the direct effect of super VA, all effects are faster than the traditional retinol effect. The anti-wrinkle effect is effective within 14 days.
Where to buy Hydroxypinacolone Retinoate Powder online?
Since the manufacturers and the concentration differ, containing Hydroxypinacolone Retinoate (HPR) powder sale also have different source. It can be easily ordered Hydroxypinacolone Retinoate (HPR) powder online from many manufacturers and suppliers.
For more professional purposes, using Hydroxypinacolone Retinoate (HPR) Powder with high purity and exceptional quality is of paramount importance. So, ordering high-quality cosmetic raw material from reliable manufacturers is beneficial.
CMOAPI is one of the certified Hydroxypinacolone Retinoate (HPR) powder manufacturers that has a long-term tradition in the industry and guarantees best-quality and well-packaged bulk Hydroxypinacolone Retinoate (HPR) powder.
Click Here To Place Your Order
Place your order here to take of CMOAPI high-quality 98% pure cosmetic raw material Hydroxypinacolone Retinoate (HPR). Our Hydroxypinacolone Retinoate (HPR) Powder is GMP and DMF certified, which is an ultimate guarantee that we deliver high-quality products to our each customers.
Reference
1. Ruth, N., and T. Mammone. “1310 Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models.” Journal of Investigative Dermatology 138.5 (2018): S223.
2.Giornale italiano di dermatologia e venereologia, 2015 Apr;150(2):143-7., Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres.
3.Giornale Italiano di Dermatologia e Venereologia, 2016/03, Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
