Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV,hepatitis B, gonorrhea, syphilis).To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.
|Solubility||nsoluble in water or alcohol, soluble in Acetic acid, ethyl ester.|
Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). Avanafil works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil is in a class of drugs called phosphodiesterase inhibitors that also includes tadalafil (Cialis powder), sildenafil (Viagra) and vardenafil (Levitra)，Dr. Wayne Hellstrom, professor of urology at Tulane University School of Medicine in New Orleans, stated in a Reuters article that Avanafil powder is potentially the fastest acting of the four,” as clinical trials have shown it can work as fast as 15 minutes.
Compare with the other ED drugs.In clinical trials, 77% of men with total erectile dysfunction who took Avanafil powder had erectile dysfunction, compared with 54% of men who took placebo. Among men with erectile dysfunction associated with diabetes, the percentage of erections achieved after taking Raw Avanafil powder was 63%, while the rate of placebo was 42%.
The dose will be different for different patients. So please follow your doctor’s orders or double check the directions on the label before taking this medicine. The following information includes only the average doses of this medicine. If your dose is different, Please dont adjust the dose without informing your doctor,Never change the dose unless your doctor tells you to do so.Otherwise it might lead to severe side effects or can’t achieve the expected effect.
Normally the recommended starting dose of avanafil is 100 mg per day taken about 30 minutes before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking medications that moderately increase the blood levels of avanafil should not exceed a total dose of 50 mg in 24 hours .Do not take avanafil more than once a day. Allow 24 hours to pass between doses，Avanafil powder can be taken with or without food.Avanafil powder can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Vardenafil powder for treatment of adult of Erectile Dysfunction
100 mg PO initially as early as 15 min before sexual activity; not to exceed 1 dose/day,
Based on individual efficacy and tolerability, the dose may be increased to 200 mg taken as early as ~15 minutes before sexual activity, or decreased to 50 mg taken ~30 minutes before sexual activity
Vardenafil powder for treatment of Renal Impairment
Mild-to-moderate (CrCl ≥30 mL/min): Dose adjustment not necessary
Severe impairment (CrCl 15-29 mL/min): Safety and efficacy not established; do not use,
Vardenafil powder for treatment of Hepatic impairment
Mild to moderate impairment: Dose adjustment not necessary
Severe impairment: Safety and efficacy not established; do not use
Commonly reported side effects of avanafil raws include: headache and flushing. Other side effects include: nasopharyngitis. See below for a more details:
Side effects not requiring immediate medical attention
Some side effects of avanafil may occur that usually do not need medical attention. These side effects of avanafil powder may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Feeling of warmth,redness of the face, neck, arms, and occasionally, upper chest
fever,sore throat,stuffy or runny nose,chills，cough producing mucus
Acid or sour stomach
body aches or pain
change in color vision
diarrhea，difficulty having a bowel movement
Side effects requiring immediate medical attention
Along with its needed effects, avanafil powder may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Please Check with your doctor immediately if any of the following side effects occur while taking avanafil:
pounding in the ears
slow or fast heartbeat
Arm, back, jaw,bladder pain
bloating or swelling of the face, arms, hands, lower legs, or feet
bloody or cloudy urine
chest pain or discomfort,chest tightness or heaviness,
difficult or labored breathing
difficult, burning, or painful urination
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