Orlistat powder
CMOAPI is a largest Orlistat powder manufacturer in China, with 1800KG capacity for per months, and own a most comprehensive of quality management system(ISO19001) and environmental management system(14001).
Orlistat powder Base Information
Name | Orlistat powder |
Appearence | White crystalline powder |
Cas | 96829-58-2 |
Assay | ≥99% |
Solubility | nsoluble in water or alcohol, soluble in Acetic acid, ethyl ester. |
Molecular Weight | 495.7 g/mol |
Melt Point | 50°C |
Molecular Formula | C9H7ClN2O5 |
Dosage | 30mg |
Storage Temp | 2-8 °C Freezer |
Grade | Pharmaceutical Grade |
Amazing and Fast Weight Loss Results On Orlistat Powder
Using purity 99.7% weight loss orlistat powder created to literally melt fat even if patients refuse to exercise! Orlistat Powder from CMOAPI manufacturer has successfully passed GMP and DMF certification, which is an ultimate guarantee that can deliver high-quality products to our each customers. And quality directly translates to happy customers, increase sales, and enhanced brand image.
What is Orlistat Powder
Orlistat powder is a drug that designed to help patients anti-obesity, the active substance is orlistat, combining Orlistat with a supervised reduced-calorie and low-fat diet, it can greatly increases its effectiveness due to its ability to block the absorption of fats in the digestive tract. So lots of weight loss market that can be seen orlistat powder uses to reduce caloric intake and fat accumulation. As a prescription drug, Orlistat be sold under brand name “Xenical”, also as an over-the-counter anti-obesity drug under the trade name “Alli”.
The clinically studies conducted on orlistat powder allowed the researchers who developed the formula to produce such a powerful weight loss compound that ugly fat is metabolized immediately and the effects are seen in just 2 weeks. Sophisticated scientific testing was necessary to discover exactly why the substance produces such amazing weight loss results.
How Does Orlistat Powder Work & Effects Is Extraordinary
Orlistat powder is a selective inhibitor that blocks the enzymes breaking down fat in the digestive tract. If we take excessive calorie intake leads to storing the redundancy as fat, will cause resulting in weight gain. Orlistat powder works by reducing the amount of fat the body absorbs from the food. Once attached to the gastric enzyme and pancreatic lipase it forms a covalent bond that prevents the enzymes from hydrolyzing dietary fat into fatty acids and monoglycerides.
Some studies show the recommended Orlistat powder dosage is 120 mg, the amount of blocked fat is about 30% of dietary fat daily. The undigested fat passes through the system and is eliminated as waste. It works by inhibiting the gastric and pancreatic lipases. These are enzymes that break down dietary fat(triglycerides) into an absorbable form, fatty acids or monoglycerides.
How to Use Orlistat Powder
The patient should simply take orlistat powder dose with water at each fat-containing main meal up to 3 times a day and up to one hour after a meal. Each meal should contain no more than 30% of its calories in fat.
Since orlistat powder has an impact on the absorption of fat-soluble vitamins like A, D, E, and K, it is highly advisable that patients take the right daily orlistat supplements to compensate for any potential deficiencies. The recommended orlistat supplement intake time is at least 2 hours before or 2 hours after taking orlistat.
This formula of orlistat powder is so effective at producing weight loss that patients can begin to see and feel the body changing in just 2 weeks! The proper treatment with orlistat Powder following the simple instructions may reverse years of overeating.
Important Caution On Orlistat Powder
Ballance is the true benefit after using orlistat powder
- Orlistat powder is created to help patients beat obesity and excessive weight. Its use by individuals aiming to become dangerously thin is to be avoided as an extremely unhealthy and risky practice.
- Despite the decrease in appetite, the patients undergoing Orlistat powder treatment must follow a healthy diet without depriving themselves of all essential nutrients.
- A complete pre-treatment examination to make sure of the normal health condition is obligatory.
- The most common Orlistat powder side effects are largely gastrointestinal and occur due to the undigested fats passing through the digestive system.
- Orlistat powder side effects occur during the first few weeks of its administration and may fade away. However, some symptoms may still persist.
- Some side effects may be caused by inappropriate orlistat powder dosage, so strictly following the prescription is essential.
- It must be strongly emphasized that increasing Orlistat powder doses does not result in more powerful effects but would rather lead to some adverse responses.
Have questions? Our experts are here and answerorlistat powder reviews
Who Benefits From Orlistat Powder?
Orlistat powder is a potent assistant to any condition requiring fast and effective elimination of excessive body fat.
1).Treating obesity enhanced with Orlistat
With 39% of the world population suffering from an excessive accumulation of fat in the body, obesity is one of the most serious public health problems recognized globally. The potential risks it involves, such as heart disorder, diabetes, certain cancers, and high blood pressure, demand taking prompt and adequate measures — planned, supervised, and controlled weight loss.
Ideally, a weight loss plan consists of a tailored diet, exercise, and where necessary medication, and is considered successful when resulting in at least 5% weight loss within a year.
Orlistat is a powerful and effective weight loss medicine that is proven to significantly contribute to achieving a loss weight goal. A study involving 3,305 overweight participants examined the effect of administering 120 mg Orlistat three times daily for 4 years combined with a low calorie, 30%-fat diet and light daily exercise. The results indicated an average weight loss of 10.6 kg for the first year. The modest weight loss ensures that patients maintain the weight or even lose more weight with a continued weight loss plan.
2). The risk of type 2 diabetes reduced with Orlistat
Type 2 diabetes or diabetes mellitus is a serious condition impairing glucose metabolism in the body. It is associated with insulin resistance or insufficient insulin production by the pancreas, and thus the inability to maintain the proper glucose levels in the body. Ignoring the early symptoms like increased thirst, unintentional weight loss, fatigue, poor vision, frequent infections, and slow-healing wounds and not addressing them properly can lead to serious complications such as hypertension, cardiovascular diseases, and heart attack. Therefore, timely and proper treatment is essential for avoiding the development of further health issues.
As a powerful weight loss drug, Orlistat powder plays a critical role in preventing the onset of type 2 diabetes. Orlistat powder effects can enhanceinsulin sensitivity, reduce postprandial plasma non-esterified fatty acids, slow or prevent the digestion of dietary fats, reduce visceral fat, and induce the secretion of glucagon-like peptide-1 in the lower small intestine.
A study on patients suffering from obesity proves the great decrease in the incidence of type 2 diabetes as a result of the treatment with orlistat accompanied by a healthy lifestyle (low-fat diet and exercise). It also resulted in great weight loss. Another study conducted with obese or overweight patients suffering from type 2 diabetes involved the administration of 120 mg Orlistat three times a day for 6 or 12 months. In addition to the weight loss effect, an improvement of glycaemic control was established, with a decrease in fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c).
All empirically obtained data confirm the efficacy of treatment with orlistat powder, combined with a mildly reduced-calorie diet, for overweight and obese patients diagnosed with type 2 diabetes.
3). Blood pressure under control with Orlistat
High blood pressure also known as hypertension is a health condition that is characterized by a systolic blood pressure ≥ 130 mm Hg or a diastolic blood pressure ≥ 80 mm Hg and affects more than 30% of the adult population worldwide. It is identified as the main risk factor for cardiovascular diseases like coronary heart disease and stroke but is also associated with heart failure, arrhythmia, chronic kidney disease, and dementia. The development of hypertension is attributed to unhealthy lifestyle choices like the lack of regular physical activity, and some health conditions like diabetes and obesity.
Inhibiting lipase, Orlistat prevents the absorption of dietary fat that could block the arteries and results in the effect of a slight blood pressure decrease.
A study investigating the effects of orlistat induced weight loss on blood pressure of 628 patients reported a significant weight loss as well as a decrease in both diastolic and isolated systolic hypertension as a result of administering 120 mg Orlistat three times a day for a year. A reduction of 9.4 mmHg in the systolic pressure and 7.7 mmHg in the diastolic pressure was recorded. In addition, the long-term of orlistat use that was found to result in slight reduction in the blood pressure by 2.5 mmHg for the systolic pressure and 1.9 mmHg for the diastolic blood pressure.
The figures obtained from the studies indicate the benefits of using Orlistat for high blood pressure treatment of obese or overweight individuals.
4). Reducing total and LDL cholesterol with Orlistat
Total cholesterol is the sum of low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, and 20% of triglycerides. Building up on the walls of blood vessels to form plaque, LDL cholesterol is responsible for narrowing the insides of the vessels and blocking blood flow. It increases health risks and is linked to conditions, such as heart disorder and stroke.
In addition to weight loss benefits, Orlistat has been reported to reduce LDL cholesterol.
A study including 294 obese or overweight patients examined orlistat effects on weight and serum lipids. The 24-week treatment involved a daily dose of 360 mg Orlistat divided into three intakes. Orlistat was found to significantly reduce weight as well as total and LDL cholesterol. It was further established that the LDL cholesterol-lowering effect was independent of the weight loss benefits. Another 6-month study covering 448 patients was devoted to identifying cholesterol-lowering effects of dietary weight loss and orlistat treatment. The results indicated a significant average weight loss of 7.4 kg. Along with that, a significant decrease in total and LDL cholesterol by 25-30 mg/dL was recorded.
Orlistat has the solid evidence-based capacity to improve conditions that can be directly or indirectly linked to obesity and excessive fat accumulation in the body. Orlistat effects are further maximized when its administration is accompanied by proper diet and exercise so that patients can benefit fully from the treatment tailored to their specific individual needs.
More Orlistat Powder Reviews who have tested
The patients that have undergone their Orlistat Treatment are delighted to look in the mirror day after day and see the visible results as unwanted fat, flab, and cellulite begin to fade away.
—“So last October I went to my doctor and I begged for help as my weight really depressed me. So he put me on orlistat and now 6 months down the line am 16kg lighter, I’ve gone from a size 18/20 to 12/14. Best thing I ever did.” – Sez, take Orlistat Powder for 1 to 6 months .
—“Started this on Xenical the 13.06.20 at 18st 9lbs and now I’m 16st 0.5lbs and lost 2st 8.5lbs so far, doesn’t work if you don’t eat well. It encourages you to eat well as you are on the toilet all the time if you don’t eat well, so far so good! It really has changed my life” – Becks, take Orlistat Powder for 1 to 6 months
—“When I started taking this drug I was 235lbs and in a matter of 4 weeks, my weight cane down to 220lbs! 15lbs in a month!! I did not even exercise, so imagine how much more is possible if I did… “ – Chris, take Orlistat Powder for 1 to 6 months.
—“I’ve been on orlistat since May 2021 and today (July 2021) I got weighed at my drs surgery and I’ve lost a whopping 2 stone in 7 weeks!! I feel fantastic and will continue to use orlistat to help me lose my weight. I haven’t really changed a lot in my diet except I’ve stopped snacking on junk!” – anonymous patient, take Orlistat Powder for 1 to 6 months.
Why To Choose Orlistat Powder From CMOAPI
We, at CMOAPI, have worked many lab hours and spent what amounts to a small fortune to make sure our Orlistat Powder meets the highest industry standards and lives up to each customer expectations. The advantages of our orlistat powder are:
- 7% purity
- GMP and DMF certification
- Guaranteed sustainable high-quality thanks to our Quality Management System.
What are your benefits from using our Orlists Powder?
- Compliance with all industry regulations related to the quality of the raw material used
- Delivering high-quality final products
- Ensuring outstanding results for the patients
- Establishing impeccable brand image
FAQ On Orlistat Powder
1.Does Orlistat powder work if the patient does not eat fat?
Orlistat powder works to reduce the amount of fat absorbed in the body. Therefore taking Orlistat with a meal without fat is ineffective and the dose should be skipped to avoid the associated orlistat side effects.
2.Can XENICAL be taken with other medications?
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases:
- Blood thinners, such as warfarin, heparin, apixaban, dabigatran and rivaroxaban
- HIV medications, such as lopinavir, ritonavir, atazanavir, efavirenz, tenofovir and emticitabine.
- Seizures medications
- Cyclosporine
- Amiodarone
- Levothyroxine
3.How long is XENICAL treatment?
Orlistat is not to be taken for more than six months over the counter (at the 60 mg dose Orlistat). If the patient has not lost at least 5% of their weight after taking Orlistat for three months, the treatment should continue.
4.Does Orlistat Powder cause liver damage?
Orlistat powder has not been identified as the direct cause of severe liver damage in both pre-clinical and clinical trials. However, some rare cases of severe Orlistat powder liver injury have been reported by people who used it.
Orlistat powder can limit the function of a vital enzyme called carboxylesterase-2 that plays an important role in detoxifying the liver, kidneys, and the whole gastrointestinal tract. When this enzyme is inhibited, serious toxicity of the vital organs may occur.
5.Where to buy Orlistat powderonline?
Since the manufacturers and the concentration differ, products containing orlistat sale have different Orlistat brand names. The lower doses of Orlistat are found as Orlistat brand names such as “Alli” and “Orlos” and can be easily ordered online from the many Orlistat powder manufacturers and suppliers.
For more professional purposes, using Orlistat Powder with high purity and exceptional quality is of paramount importance. So, ordering high-quality weight loss raw material from reliable manufacturers is beneficial.
CMOAPI is one of the certified Orlistat powder manufacturers that has a long-term tradition in the industry and guarantees best-quality and well-packaged bulk orlistat powder.
Click Here To Place Your Order
Place your order here to take of CMOAPI high-quality 99.7% pure Weight Loss Orlistat Powder created to literally melt fat. Our Orlistat Powder is GMP and DMF certified, which is an ultimate guarantee that we deliver high-quality products to our each customers.
References
- “US orlistat label” (PDF). FDA. August 2015. Retrieved 18 April 2018. For label updates see FDA index page for NDA 020766
- Barbier P, Schneider F (1987). “Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin”. Helvetica Chimica Acta. 70 (1): 196–202. doi:10.1002/hlca.19870700124.
- Bodkin J, Humphries E, McLeod M (2003). “The total synthesis of (−)-tetrahydrolipstatin”. Australian Journal of Chemistry. 56 (8): 795–803. doi:10.1071/CH03121.
- Filippatos, Theodosios & Derdemezis, Christos & Gazi, Irene & Nakou, Eleni & Mikhailidis, Dimitri & Elisaf, Moses. (2008). Orlistat-Associated Adverse Effects and Drug Interactions. Drug safety: an international journal of medical toxicology and drug experience. 31. 53-65. 10.2165/00002018-200831010-00005.
- Sharma, A. M., & Golay, A. (2002). Effect of orlistat-induced weight loss on blood pressure and heart rate in obese patients with hypertension. Journal of hypertension, 20(9), 1873–1878. doi.org/10.1097/00004872-200209000-00034.
- Stylized with a lowercase a on the packaging, and a bar over the i (that is, “allī”), but capitalized conventionally in the manual.
- Zhi J, Melia AT, Eggers H, Joly R, Patel IH (1995). “Review of limited systemic absorption of orlistat, a lipase inhibitor, in healthy human volunteers”. J Clin Pharmacol. 35 (11): 1103–8. doi:10.1002/j.1552-4604.1995.tb04034.x. PMID 8626884.
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